Notes about blc files, written as part of the primary analysis of Illumina sequencing machines.
Sequence uniqueness within the genome plays an important part when attempting to map short sequence parts – e.g. next-generation short sequencing reads. It is one of the factors that can introduce a bias in sequencing or it’s analysis – the other important factor being GC content (GC-rich sequences, eg. genic/exonic region, as well as very […]