Read-counting for PGT-A

Introductory article about Pre-Implantation "Genetic Testing for Aneuploidy" using sequencing-based read-counting.

RNA-Seq data quality scores

There are different ways to encode the quality scores in FASTQ files from Next-generation sequencing machines. This…

Determining Coverage for NGS Data

One of the most common question after your Next-Generation Sequencing (NGS) run is: "What is…

Command-line NGS data munging

Notes about working with fasta / fastq files on the Unix command line.

A DNA Sequencing History

Some of the landmarks in the history of DNA sequencing and molecular biology.