This is a collection of notes that I (Felix Kokocinski) took working on various topics in bioinformatics, genome biology, etc. They are here to remind myself – and maybe others in similar situations.This is a personal site, not related to current or past employers. The ideas shown here might not be suitable for your requirements, […]
Small changes in the sequence of human chromosomes can have detrimental effects in the person’s health and development. The often affect multiple genes but are too small to be visible with traditional karyotyping methods. These changes seem to appear near regions of low complexity (repetitive sequence regions) with some consistency as novel mutations. The following […]
Some information on what technology I found useful for doing my work for different projects as a consulting bioinformatics scientist.
The phase (or sometimes called frame) gives information on how to translate individual parts of a gene, the coding exons. Phases 1 & 2 have a different definition in GFF and EnsEMBL format!
As the largest cloud computing company Amazon Web Services (AWS) offers various options to use compute-power on an “as-needed” basis. You can choose what size and type of machine, what number of machines – and you can choose a price model where you are “bidding” for the resource.